Treatment for COVID-19 Infection


This page has been automatically translated from English. MSDH has not reviewed this translation and is not responsible for any inaccuracies.

If you test positive for COVID-19 and may be at higher risk for severe illness, ask your doctor about treatment to prevent serious illness and hospitalization.

Healthcare Provider Resources

Vaccination and boosters are the best tool we have to protect people and communities from COVID-19. Since COVID-19 vaccination began, most Mississippi COVID-19 deaths are among people not fully vaccinated. Learn more

What treatments are available for COVID-19?

Oral Antivirals

Ages 12 and up are eligible for treatment with Paxlovid.

Oral antiviral therapies Paxlovid (Pfizer) and molnupiravir (Merck) are products authorized by the FDA for treatment of COVID-19. These therapies require a prescription from a licensed healthcare provider. Talk to your healthcare provider or pharmacist to see whether an oral antiviral is the right option for you.

How they work: Oral antiviral medications work by targeting specific proteins on the SARS-CoV-2 virus to help prevent the virus replicating within the body. It is important that the oral antiviral is started within 5 days of the start of symptoms.

Monoclonal Antibodies

The monoclonal antibody bebtelovimab (Eli Lilly) is a product authorized by the FDA for treatment of COVID-19. This treatment requires an order from a licensed and authorized healthcare provider and must also be administered by a qualifying healthcare provider. Talk to your healthcare provider to see whether a monoclonal antibody is the right option for you.

How they work: Your body naturally makes antibodies to fight infection. However, your body may not have antibodies designed to recognize a new virus like the one that causes COVID-19.

Monoclonal antibodies, or mAbs, are made in a laboratory to fight a particular infection, based on natural antibodies against COVID-19. mAb treatment can help patients who are at high risk for severe symptoms or hospitalization from COVID-19.


Evusheld is a monoclonal antibody use for prevention in individuals with weakened immune systems, such as cancer treatment patients.

Who can receive treatment?

People who test positive for COVID-19 with mild to moderate symptoms who are at higher risk for developing more serious COVID-19 symptoms may be eligible for monoclonal antibody or oral antiviral treatment, depending on their health history and exposure to COVID-19, and how long they've had symptoms of COVID-19.

Cost: The monoclonal antibody bebtelovimab and the oral antivirals Paxlovid and molnupiravir are provided free from the federal government. Coverage of fees for administration or dispensing depends on your specific health insurance policy.

Where can I receive treatment?

These therapies require a prescription by a licensed and authorized provider. Patients should coordinate with their healthcare provider prior to contacting a location to receive these therapies. Pharmacists may now provide Paxlovid directly to eligible patients without a doctor's prescription.

Monoclonal Antibodies

If you have tested positive for COVID-19, contact your doctor or a healthcare provider about receiving treatment with monoclonal antibodies.

Oral Antivirals

Locate Medications

Use this interactive map to locate a facility that can provide oral antiviral or monoclonal antibody medication.

Last reviewed on Feb 11, 2022
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