Premature births are a major public health challenge in Mississippi. Prematurity puts newborns at risk for health and developmental problems as they grow, and is a leading cause of early death.
The Challenge for Mississippi
In 2024, about one in 7 babies were born prematurely — before a full 39 weeks
of pregnancy. This continues a gradually increasing trend of premature births in the state over the last ten years.
Mississippi had the highest rate of premature births in the U.S. in 2024.
Leading contributors to premature birth are mothers with high blood pressure or who are obese. Healthy mothers are the best way to reduce premature births.
Giving Babies a Healthy Start
Mothers-to-be can give their babies the best start in life by:
- Staying in good overall health, including keeping a healthy weight and getting regular physical exercise.
- Quitting smoking, and making sure that others in your household do not smoke.
- Getting regular prenatal care from a doctor, and following their recommendations for medication and lifestyle.
Even women who are not currently planning to become pregnant should stay healthy since half of all pregnancies are unplanned.
Find Out More
- Steps to Take for a Healthy Pregnancy
- 2025 March of Dimes report card on maternal health for Mississippi
For more information about Maternal and Child Health Programs and the MCH Block Grant, call 1-800-721-7222.
Your input is important. We want to hear from you about maternal and child health needs, the MCH Block Grant, and programs in Mississippi. Take a moment to share your comments, ideas and concerns with us.

